
Across the world from Silicon Valley, a few brave entrepreneurs are doing excellent work around Southeast Asia’s Mekong River. The effects of their work go far beyond fattening some VC’s portfolios.
Unlike most Silicon Valley startups, the businesses participating in the Mekong Innovative Startups in Tourism (MIST) Program don’t dream of hefty dividends and billions of dollars in preferred shares. Instead, they aim to make a difference in one of the world’s most challenging tourism environments.
The Greater Mekong Subregion (GMS) – a grouping of countries along the Mekong River that include Myanmar, Cambodia, Thailand, Vietnam and Laos – has “experienced a period of explosive growth, to the point that this is the fastest growing region for inbound tourism in the world,” explained MIST’s Director Jason Lusk at last month’s Mekong Tourism Forum at Nakhon Phanom, Thailand.
“That growth masks the fact that we’ve got a long way to go.”

Overcoming the Mekong Sub-Region’s Travel Hurdles
Countries in the GMS consistently fail to rank among the world’s most-visited destinations. Consistently, even as it boasts popular stops like Angkor Wat and Luang Prabang.
“The [local] travel industry, for all of the hype in the region, is statistically one of the least, if not the least efficient industries in Southeast Asia,” Jason explained.
Travel entrepreneurs face many hurdles: lack of online presence that keeps them invisible to travelers googling for future trips; unevenly distributed tour itineraries that crowd some places and deprive the rest; and growing plastic pollution, among others.
In this challenging environment, “[businesses need] to learn to operate more effectively, to be more profitable, to serve tourists better,” Jason explained. “That’s the reason the MIST program exists – we’re trying to inspire this type of innovation.”
Money… and Brains
MIST is on its second year of nurturing Mekong-based startups. Over 350 entrepreneurs applied to join this year, all undergoing an extremely competitive process to pick out the ten who presented to us at the Mekong Tourism Forum.
Even with its short track record, MIST has already succeeded in bridging Mekong startups with capital infusions and a significant brain trust.
Jason reminds us of I Love Asia (I Love Hue) Tour, which made last year’s final round.
I Love Hue offers women-led motorbike tours in Hoi An and Hue, Vietnam. Their winning pitch caught the attention of Facebook’s COO Sheryl Sandberg.
“When she came to Vietnam last year, she asked to meet [Nguyen Thi Huong Lien], the CEO of I Love Asia tour – who by the way is just 24 years old!” Jason told us. “They talked for half an hour, and Sheryl had to be torn away from the meeting by her staff. The two of them since then have had a lively email correspondence.
“I know a lot of great accelerator programs in the GMS, but which other accelerator program has attracted Sheryl Sandberg as a match-up?” Jason asked the audience. “I think we’re the only one.”

Winning Startups Must Solve Tourism Problems
Entrepreneurs can choose to join through one of two streams.
The Startup Accelerator gives a boost to early-stage travel and hospitality startups. And the Market Access program attracts more mature innovators looking to expand in the Mekong region. (Only Mekong based companies may apply to the first one. The second is open to any business with Mekong-based operations.)
For the Accelerator program, its five most outstanding startups win innovation grants of up to $10,000 and an opportunity to pitch to investors at Singapore’s ITB Asia.
Businesses that catch MIST’s attention must, above all, “solve problems,” explained Jens Thraenhart, the Mekong Tourism Coordinating Office (MTCO)’s Executive Director. “Many of [these startups] may leverage technology, but most important to us is that they’re solving problems – ground transportation, visitor facilitation, and environmental problems like pollution of single use plastic items.”
Of the ten startups we encountered at Nakhon Phanom, we found four with greater-than-usual potential for making a positive change in the Mekong.
We’ll meet our first two choices in the next blog installment. The first: a Lao citizen using reusable straws to face down a mounting Mekong garbage problem. The second: a Vietnamese digital nomad leading fellow nomads in “workations” across her homeland.
Fantastic post, really detailed and gives an excellent insight into what MIST is all about! I actually missed this at the forum so found your post really interrsting
Greeting from I Love Asia Tour!
I’m Erin from I Love Vietnam Tour company and as you might remember it is Ms.Lien Nguyen’s company that you mentioned in this article.
I’d love to introduce our new website https://iloveasiatour.com. We had gone abroad and now become I Love Asia Tour. We have shut down I Love Hue Tour website so the link in your blog post is now unavailable. I’m wondering if you can replace that dead link with our new one which is https://iloveasiatour.com?
Thank you for reading my comment!
Erin and I Love Asia Tour team
Hi Erin, Sorry for the delayed reply! (Spam filter). I’ve updated the link. Thanks!